Allopurinol Cost Calculator
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Estimate your out-of-pocket expenses for 300 mg allopurinol based on your location and insurance coverage
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- Base prescription cost $0.00
- Insurance adjustment $0.00
- Dispensing fee $0.00
Quick Takeaways
- Allopurinol is the most prescribed drug for gout, and its price varies widely by country and pharmacy.
- Generic versions cost far less than brand‑name equivalents, but insurance coverage can close the gap.
- Typical out‑of‑pocket expenses in Australia range from AU$5 to AU$30 per month, while U.S. patients may pay US$30‑US$150.
- Strategies like bulk fills, PBS‑eligible prescriptions, and reputable online pharmacies can shave up to 60% off the retail price.
- Understanding the pricing components-manufacturing, dispensing fees, taxes, and rebates-helps you negotiate a fair cost.
What Is Allopurinol?
When it comes to gout, Allopurinol is a xanthine oxidase inhibitor that reduces uric acid production, preventing painful flare‑ups. It’s been the cornerstone of long‑term gout management since the 1960s and is listed on the WHO Essential Medicines List. The drug works by blocking the enzyme that converts purines to uric acid, keeping serum levels below the 6mg/dL threshold most clinicians recommend.
Allopurinol is sold both as a generic and under brand names such as Zyloprim (the original US brand). The generic version contains the same active ingredient, 300mg of allopurinol per tablet, but typically costs a fraction of the brand price.
How Is Allopurinol Priced?
Pharmacy pricing for any medication, including Allopurinol (generic form), is a blend of several factors:
- Manufacturing cost: bulk synthesis of the active pharmaceutical ingredient (API) drives base price.
- Regulatory fees: approvals, quality‑control audits, and market‑entry fees add overhead.
- Dispensing fee: pharmacies charge a fixed amount for each prescription filled, varying by chain and location.
- Taxes and GST: GST (10% in Australia) is applied to the final retail price.
- Rebates and subsidies: government programs (e.g., PBS in Australia, Medicaid in the US) may reimburse part of the cost.
Because allopurinol is an older, off‑patent drug, manufacturing costs are relatively low, but the final price still depends on local market dynamics and insurance negotiations.

Price Comparison by Country
Country | Typical retail price (per month) | Insurance‑adjusted price | Notes |
---|---|---|---|
Australia | AU$15‑AU$30 | AU$5‑AU$12 (PBS subsidised) | PBS covers 85% of cost for eligible patients. |
United States | US$45‑US$150 | US$20‑US$60 (depending on tier) | Prices vary by pharmacy chain; Medicare Part D may lower cost. |
United Kingdom | £12‑£25 | £4‑£8 (NHS prescription exemption) | NHS provides a flat prescription charge; low‑income patients exempt. |
Canada | CA$25‑CA$45 | CA$10‑CA$20 (provincial drug plans) | Provincial formularies influence reimbursement levels. |
India | INR120‑INR250 | INR80‑INR150 (state‑run schemes) | Generic market is highly competitive, keeping prices low. |
These figures represent the cost of a 30‑day supply of 300mg tablets, which is the most common dosage for maintenance therapy. Prices for higher doses or extended‑release formulations can be 30‑50% higher.
Insurance & Out‑of‑Pocket Costs
Health insurance (public or private plans that reimburse medication expenses) dramatically changes what you actually pay. In Australia, the Pharmaceutical Benefits Scheme (PBS) provides a co‑payment of AU$6.80 for most patients, dropping to AU$2.80 for concessional beneficiaries. In the U.S., a typical Medicare Part D plan might place allopurinol in Tier2, resulting in a co‑payment of US$10‑US$25 per month after meeting the deductible.
Understanding the difference between a co‑payment (the fixed amount you pay at the pharmacy) and the total prescription price is key. Some insurers apply a percentage‑based coinsurance instead of a flat co‑pay, which can push out‑of‑pocket costs higher if the retail price spikes.
For patients without coverage, bulk‑ordering a 90‑day supply often cuts the per‑tablet price by 20‑30%. Some pharmacies also offer discount cards that lower the retail price to a level comparable with insured rates.

Tips to Lower Your Bill
Here are proven ways to keep the Allopurinol price from draining your wallet:
- Ask for the generic. Pharmacists can substitute brand‑name Zyloprim with generic allopurinol at no extra cost.
- Check PBS eligibility. If you’re an Australian resident, apply for concessional status to reduce the co‑payment.
- Shop around. Large‑chain pharmacies often have negotiated discounts that smaller independents can’t match.
- Use a 90‑day prescription. Many insurers waive the dispensing fee for extended supplies.
- Explore therapeutic alternatives. If allopurinol isn’t covered, drugs like Febuxostat (a non‑purine xanthine oxidase inhibitor) may be reimbursed at a lower tier.
- Apply discount programs. Platforms such as GoodRx (US) or Pharmacy Discounts (AU) provide printable coupons.
Cost‑Saving Checklist
- Confirm you have a valid prescription (a doctor's order for medication) on file.
- Verify if your plan covers the generic version.
- Ask your pharmacist if a 30‑day or 90‑day supply is more economical.
- Check for government subsidies (PBS, NHS, Medicaid).
- Compare at least three local pharmacies or online options.
- Look for reputable discount coupons before checkout.
- Review your insurance statements for unexpected co‑payment changes.
Frequently Asked Questions
Is the generic version of allopurinol as effective as the brand name?
Yes. The generic contains the same active ingredient, dosage strength, and bioequivalence profile as Zyloprim. Regulatory agencies require that generics meet strict quality standards, so effectiveness and safety are identical.
Can I get allopurinol over the counter?
No. Allopurinol is a prescription‑only medication in virtually all countries because dosage must be tailored to blood urate levels and kidney function.
How often should I refill my prescription?
Most clinicians prescribe a 30‑day supply for dose titration, then switch to a 90‑day supply once the dose is stable. Check with your doctor and pharmacy for the best interval.
What factors cause price differences between countries?
Key drivers include government price‑setting (e.g., PBS in Australia), local manufacturing costs, market competition, taxes, and the presence of insurance subsidies. Countries with strong price controls usually see lower consumer costs.
Are there any hidden fees when buying allopurinol online?
Reputable online pharmacies disclose shipping, handling, and any applicable GST. Be wary of sites that hide extra charges or require unusual payment methods; they may be operating outside regulatory oversight.